OA-5 launched for another cargo resupply mission to the International Space Station on October 17th, 2016. This was the fifth successful mission from MARS Pad 0A since the Antares program began launching from the pad in 2013. OA-5 was the first launch of the Antares 230 vehicle from Pad 0A.

The Cygnus spacecraft aboard OA-5 was named the S.S. Alan Poindexter.

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